Content
Cascaded Photoinduced Drug Delivery to Cells from Multifunctional Core–Shell Mesoporous Silica
02.05.2012
Advanced Healthcare Materials,
2012,
DOI: 10.1002/adhm.201100033,
Volume 1, Issue 3, pages 316–320
published on 02.05.2012
Advanced Healthcare Materials, online article
Advanced Healthcare Materials, online article
Different bioactive molecules are released into living cells from lipid-covered mesoporous silica nanoparticles. The release is triggered by light, as the particles feature covalently attached photosensitizers as membrane-opening agents. It is demonstrated that the particles achieve endosomal escape and that they release their cargo into the cytosol.
