Research Area C

2013

2012

  Translation Elongation Factor EF-P Alleviates Ribosome Stalling at Polyproline Stretches
  Funktionalisierung αvβ3- oder α5β1-selektiver Integrinantagonisten für die Oberflächenbeschichtung: ein Hilfsmittel zur Unterscheidung von Integrinsubtypen in vitro
  Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 30-splice site recognition
  N-Methylierung von Peptiden und Proteinen: ein wichtiges Element für die Regulation biologischer Funktionen
  Optimal degree of protonation for 1H detection of aliphatic sites in randomly deuterated proteins as a function of the MAS frequency
  Structural basis for TetM-mediated tetracycline resistance
  Structural Properties of EGCG-Induced, Nontoxic Alzheimer's Disease Aβ Oligomers
  A Conformationally Frozen Peptoid Boosts CXCR4 Affinity and Anti-HIV Activity
  Behavior of primary human osteoblasts on trimmed and sandblasted Ti6Al4V surfaces functionalized with integrin avb3-selective cyclic RGD peptides
  CTD Tyrosine Phosphorylation Impairs Termination Factor Recruitment to RNA Polymerase II
  Intestinal Permeability of Cyclic Peptides: Common Key Backbone Motifs Identified
  Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples
  A Movie of RNA Polymerase II Transcription
  Cell adhesion and proliferation on RGD-modified recombinant spider silk proteins
  MC EMiNEM Maps the Interaction Landscape of the Mediator
  Dynamics in multi-domain protein recognition of RNA
  Structure of Mre11–Nbs1 complex yields insights into ataxia-telangiectasia–like disease mutations and DNA damage signaling
  Lys34 of translation elongation factor EF-P is hydroxylated by YfcM
  EMBO welcomes 3 CIPSM scientists as new members
  An Asymmetric Dimer as the Basic Subunit in Alzheimer’s Disease Amyloid β Fibrils
  Swi2/Snf2 remodelers: hybrid views on hybrid molecular machines
  Mechanism of Translesion Transcription by RNA Polymerase II and Its Role in Cellular Resistance to DNA Damage
  Structural and Functional Organization of the Ska Complex, a Key Component of the Kinetochore-Microtubule Interface
  Comparative Dynamic Transcriptome Analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation
  Substrate Transport Activation Is Mediated through Second Periplasmic Loop of Transmembrane Protein MalF in Maltose Transport Complex of Escherichia coli
  Dynamic Architecture of a Minimal RNA Polymerase II Open Promoter Complex
  Crosslinking-MS analysis reveals RNA polymerase I domain architecture and basis of rRNA cleavage
  Radiolabelled RGD peptides for imaging and therapy
  Structural basis of highly conserved ribosome recycling in eukaryotes and archaea
  Solid-phase-assisted synthesis of targeting peptide–PEG–oligo(ethane amino)amides for receptor-mediated gene delivery
  Conservation between the RNA Polymerase I, II, and III Transcription Initiation Machineries
  Target- and Resistance-Based Mechanistic Studies with TP-434, a Novel Fluorocycline Antibiotic
  A structural perspective on Mediator function
  hnRNP A1 Proofreads 30 Splice Site Recognition by U2AF
  Synthesis of N-methylated cyclic peptides
  Processive RNA decay by the exosome
  Characterization of Membrane Proteins in Isolated Native Cellular Membranes by Dynamic Nuclear Polarization Solid-State NMR Spectroscopy without Purification and Reconstitution
  Synthesis and Conformational Analysis of Efrapeptins
  Chromodomains read the arginine code of post-translational targeting
  The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop
  Solution Structure and Molecular Interactions of Lamin B Receptor Tudor Domain
  Structural and Mechanistic Implications of Metal-Binding in the Small Heat-Shock Protein αB-Crystallin
  Ultra-high resolution in MAS solid-state NMR of perdeuterated proteins: Implications for structure and dynamics
  Sensing of viral nucleic acids by RIG-I: From translocation to translation

2011

  On the specificity of antibiotics targeting the large ribosomal subunit
  Tailoring of Integrin Ligands: Probing the Charge Capability of the Metal Ion-Dependent Adhesion Site
  Spectroscopically Well-Characterized RGD Optical Probe as a Prerequisite for Lifetime-Gated Tumor Imaging
  Assignment strategies for aliphatic protons in the solid-state in randomly protonated proteins
  Structural basis for dimethylarginine recognition by the Tudor domains of human SMN and SPF30 proteins
  The DARC site: a database of aligned ribosomal complexes
  The RIG-I ATPase domain structure reveals insights into ATP-dependent antiviral signalling
  Increasing αvβ3 Selectivity of the Anti-Angiogenic Drug Cilengitide by N-Methylation
  Increasing alpha-v-beta-3 Selectivity of the Anti-Angiogenic Drug Cilengitide by N-Methylation
  Structure of human mitochondrial RNA polymerase
  Molecular basis of Rrn3-regulated RNA polymerase I initiation and cell growth
  ATP driven structural changes of the bacterial Mre11:Rad50 catalytic head complex
  A Glycopeptide Dendrimer Inhibitor of the Galactose-Specific Lectin LecA and of Pseudomonas aeruginosa Biofilms
  Design, Synthesis, and Functionalization of Dimeric Peptides Targeting Chemokine Receptor CXCR4
  Introducing Lasso Peptides as Molecular Scaffolds for Drug Design: Engineering of an Integrin Antagonist
  Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53
  Nuclear actin-related proteins take shape
  Strategies for the structural analysis of multi-protein complexes: Lessons from the 3D-Repertoire project
  Telethonin Deficiency Is Associated With Maladaptation to Biomechanical Stress in the Mammalian Heart
  1H, 13C, 15N and 31P chemical shift assignments of a human Xist RNA A-repeat tetraloop hairpin essential for X-chromosome inactivation
  PET Imaging of CXCR4 Receptors in Cancer by a New Optimized Ligand
  Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF
  Structure and mechanism of the Swi2/Snf2 remodeller Mot1 in complex with its substrate TBP
  Evolution of Two Modes of Intrinsic RNA Polymerase Transcript Cleavage
  Differential Effects of Thiopeptide and Orthosomycin Antibiotics on Translational GTPases
  Optimal 2H rf Pulses and 2H–13C Cross-Polarization Methods for Solid-State 2H MAS NMR of Perdeuterated Proteins
  A Conformational Switch Underlies ClpP Protease Function
  Proton-Detected Solid-State NMR Spectroscopy of Fibrillar and Membrane Proteins
  1H, 13C and 15N chemical shift assignments of IPSEΔNLS
  Iwr1 Directs RNA Polymerase II Nuclear Import
  Cryo-EM structure of the ribosome–SecYE complex in the membrane environment
  The Effect of Multiple N-Methylation on Intestinal Permeability of Cyclic Hexapeptides
  Structural biochemistry of nuclear actin-related proteins 4 and 8 reveals their interaction with actin
  Mediator head subcomplex Med11/22 contains a common helix bundle building block with a specific function in transcription initiation complex stabilization
  N-Methylated sst2 Selective Somatostatin Cyclic Peptide Analogue as a Potent Candidate for Treating Neurogenic Inflammation
  A Cytoplasmic Complex Mediates Specific mRNA Recognition and Localization in Yeast
  The Mre11:Rad50 Structure Shows an ATP-Dependent Molecular Clamp in DNA Double-Strand Break Repair
  Structural Analysis of Large Protein Complexes Using Solvent Paramagnetic Relaxation Enhancements
  Structure Calculation from Unambiguous Long-Range Amide and Methyl 1H−1H Distance Restraints for a Microcrystalline Protein with MAS Solid-State NMR Spectroscopy
  Take a look at Karl-Peter Hopfner's "Sensing DNA Damage" Cell Movie
  NMR and small-angle scattering-based structural analysis of protein complexes in solution
  Architecture of the RNA polymerase–Spt4/5 complex and basis of universal transcription processivity
  Structure and VP16 binding of the Mediator Med25 activator interaction domain
  Structural basis of RNA polymerase II backtracking, arrest and reactivation
  Bacterial Inclusion Bodies of Alzheimer’s Disease b-Amyloid Peptides Can Be Employed To Study Native-Like Aggregation Intermediate States
  The ribosomal tunnel as a functional environment for nascent polypeptide folding and translational stalling
  Peptides in the Ribosomal Tunnel Talk Back
  SecM-Stalled Ribosomes Adopt an Altered Geometry at the Peptidyl Transferase Center
  PET Imaging of Integrin alpha-V-beta-3 Expression
  Dynamic transcriptome analysis measures rates of mRNA synthesis and decay in yeast
  Stable functionalized PEGylated quantum dots micelles with a controlled stoichiometry
  pH-Dependent Dimerization and Salt-Dependent Stabilization of the N-terminal Domain of Spider Dragline Silk-Implications for Fiber Formation
  Proteomic Characterization of Archaeal Ribosomes Reveals the Presence of Novel Archaeal-Specific Ribosomal Proteins

2010

  Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry
  Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites
  Structure and DNA-binding activity of the Pyrococcus furiosus SMC protein hinge domain
  CIPSM's Daniel Wilson received the EMBO Young Investigators Award for his work on new antibiotics
  RNA polymerase II–TFIIB structure and mechanism of transcription initiation
  Reversible and Controllable Nanolocomotion of an RNA-Processing Machinery
  Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome
  Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution
  Mechanism of replication blocking and bypass of Y-family polymerase Eta by bulky acetylaminofluorene DNA adducts
  The transcription elongation factor Bur1-Bur2 interacts with replication protein A and maintains genome stability during replication stress
  NCO-sP(EO-stat-PO) surface coatings preserve biochemical properties of RGD peptides
  NES consensus redefined by structures of PKI-type and Rev-type nuclear export signals bound to CRM1
  Optimized Measurement Temperature Gives Access to the Solution Structure of a 49 kDa Homohexameric Beta - Propeller
  Structural Basis for Translational Stalling by Human Cytomegalovirus and Fungal Arginine Attenuator Peptide
  A tandem SH2 domain in transcription elongation factor Spt6 binds the phosphorylated RNA polymerase II CTD
  Molecular Basis of RNA Polymerase III Transcription Repression by Maf1
  Polymeric Substrates with Tunable Elasticity and Nanoscopically Controlled Biomolecule Presentation
  Uniform transitions of the general RNA polymerase II transcription complex
  Hsp12 Is an Intrinsically Unstructured Stress Protein that Folds upon Membrane Association and Modulates Membrane Function
  RNA Polymerase I Contains a TFIIF-Related DNA-Binding Subcomplex
  Structural Basis for Adenylate Kinase Activity in ABC ATPases
  Structure of an atypical Tudor domain in the Drosophila Polycomblike protein
  Improvement of drug-like properties of peptides: the somatostatin paradigm
  Structural Basis for Homodimerization of the Src-associated during Mitosis, 68-kDa Protein (Sam68) Qua1 Domain
  Probing Translation with Small-Molecule Inhibitors
  The archaeo-eukaryotic primase of plasmid pRN1 requires a helix bundle domain for faithful primer synthesis
  Interplay between the Ribosomal Tunnel, Nascent Chain, and Macrolides Influences Drug Inhibition
  Nucleocytoplasmic shuttling of the La motif-containing protein Sro9 might link its nuclear and cytoplasmic functions
  Towards molecular systems biology of gene transcription and regulation
  Multiple N-Methylation of MT-II Backbone Amide Bonds Leads to Melanocortin Receptor Subtype hMC1R Selectivity: Pharmacological and Conformational Studies
  A conserved spider silk domain acts as a molecular switch that controls fibre assembly
  Structural Analysis of Protein Interfaces from 13C Direct-Detected Paramagnetic Relaxation Enhancements
  Cilengitide: The First Anti-Angiogenic Small Molecule Drug Candidate. Design, Synthesis and Clinical Evaluation
  Structure and RNA recognition by the snRNA and snoRNA transport factor PHAX
  Quantitative analysis of processive RNA degradation by the archaeal RNA exosome
  The Impact of Amino Acid Side Chain Mutations in Conformational Design of Peptides and Proteins
  Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif
  Cell Adhesion Strength Is Controlled by Intermolecular Spacing of Adhesion Receptors
  Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1
  An Efficient Protocol for NMR-Spectroscopy-Based Structure Determination of Protein Complexes in Solution
  α-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel
  Structure and DNA binding activity of the mouse condensin hinge domain highlight common and diverse features of SMC proteins
  Preparation and topology of the Mediator middle module
  BclxL Changes Conformation upon Binding to Wild-type but Not Mutant p53 DNA Binding Domain
  Coupled chaperone action in folding and assembly of hexadecameric Rubisco
  Imaging of integrin avb3 expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography
  The Transmembrane Structure of Integrin aIIbb3: Significance for Signal Transduction
  Force-induced destabilization of focal adhesions at defined integrin spacings on nanostructured surfaces

2009

  Modulation of protein properties in living cells using nanobodies
  PSRP1 Is Not a Ribosomal Protein, but a Ribosome-binding Factor That Is Recycled by the Ribosome-recycling Factor (RRF) and Elongation Factor G (EF-G)
  Structural Insight into Nascent Polypeptide Chain–Mediated Translational Stalling
  Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome
  The A–Z of bacterial translation inhibitors
  Biosynthesis of the Aminocyclitol Subunit of Hygromycin A in Streptomyces hygroscopicus NRRL 2388
  Identification of Distinct Thiopeptide-Antibiotic Precursor Lead Compounds Using Translation Machinery Assays
  X-ray structure of Pur-α reveals a Whirly-like fold and an unusual nucleic-acid binding surface
  Lessons from structural and biochemical studies on the archaeal exosome
  Enhanced SnapShot: Antibiotic Inhibition of Protein Synthesis II
  DNA Double-Strand Breaks Come into Focus
  A Boost for Sequence Searching
  SnapShot: Antibiotic Inhibition of Protein Synthesis I
  The torpedo nuclease Rat1 is insufficient to terminate RNA polymerase II in vitro
  Molecular basis of transcriptional mutagenesis at 8-oxoguanine
  The Final Step of Hygromycin A Biosynthesis, Oxidation of C-5''-Dihydrohygromycin A, Is Linked to a Putative Proton Gradient-Dependent Efflux
  Formation of She2p tetramers is required for mRNA binding, mRNP assembly, and localization
  Hsp90 is regulated by a switch point in the C-terminal domain
  Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences
  Prolonged stability by cyclization: Macrocyclic phosphino dipeptide isostere inhibitors of b-secretase (BACE1)
  Helical Growth of the Arabidopsis Mutant tortifolia2 Does Not Depend on Cell Division Patterns but Involves Handed Twisting of Isolated Cells
  mRNA Export - An Integrative Component of Gene Expression
  Nano positioning system reveals the course of upstream and nontemplate DNA within the RNA polymerase II elongation complex
  Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II
  Structural Basis of Transcription: Mismatch-Specific Fidelity Mechanisms and Paused RNA Polymerase II with Frayed RNA
  Unusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2.
  Fast and accurate automatic structure prediction with HHpred
  An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies
  Adhesion Dance with Raver
  Breaking the Dogma of the Metal-Coordinating Carboxylate Group in Integrin Ligands: Introducing Hydroxamic Acids to the MIDAS To Tune Potency and Selectivity
  Ligands for Mapping αvβ3-Integrin Expression in Vivo
  A movie of the RNA polymerase nucleotide addition cycle
  Structure and in Vivo Requirement of the Yeast Spt6 SH2 Domain
  HHomp—prediction and classification of outer membrane proteins
  Non-Hydrolyzable RNA-Peptide Conjugates: A Powerful Advance in the Synthesis of Mimics for 3-Peptidyl tRNA Termini
  The HSP90 binding mode of a radicicol-like E-oxime determined by docking, binding free energy estimations, and NMR 15N chemical shifts
  Interaction of human heat shock protein 70 with tumor-associated peptides
  Sequence context-specific profiles for homology searching
  Cytosolic Viral Sensor RIG-I Is a 5′-Triphosphate–Dependent Translocase on Double-Stranded RNA
  Structure and Ligand Binding of the Extended Tudor Domain of D. melanogaster Tudor-SN
  Impact of Order and Disorder in RGD Nanopatterns on Cell Adhesion
  The regulatory domain of the RIG-I family ATPase LGP2 senses double-stranded RNA
  Structural basis for competitive interactions of Pex14 with the import receptors Pex5 and Pex19
  Structure–function studies of the RNA polymerase II elongation complex
  Time-Resolved Binding of Azithromycin to Escherichia coli Ribosomes
  Less Is More for Leaderless mRNA Translation
  The Native 3D Organization of Bacterial Polysomes
  A Distinct Mode of Interaction of a Novel Ketolide Antibiotic That Displays Enhanced Antimicrobial Activity
  Thioredoxin as a fusion tag for carrier-driven crystallization

2008

  MicroRNAs Repress Mainly through mRNA Decay
  RNA polymerase fidelity and transcriptional proofreading
  The archaeal RNA polymerase subunit P and the eukaryotic polymerase subunit Rpb12 are interchangeable in vivo and in vitro
  Identification, structure, and functional requirement of the Mediator submodule Med7N/31
  Cooperativity in Adhesion Cluster Formation during Initial Cell Adhesion
  Phospholipid scramblases and Tubby-like proteins belong to a new superfamily of membrane tethered transcription factors
  Cell interactions with hierarchically structured nano-patterned adhesive surfaces
  A NMR strategy to unambiguously distinguish nucleic acid hairpin and duplex conformations applied to a Xist RNA A-repeat
  Can N-methylated amino acids serve as substitutes for prolines in conformational design of cyclic pentapeptides?
  Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2
  Dimerization and Protein Binding Specificity of the U2AF Homology Motif of the Splicing Factor Puf60*
  The Solution Structure of BMPR-IA Reveals a Local Disorder-to-Order Transition upon BMP-2 Binding
  Ulrike Gaul comes to CIPSM! Germany, Munich – the house is rocking.
  Screening of fusion partners for high yield expression and purification of bioactive viscotoxins
  A nano-positioning system for macromolecular structural analysis
  Deuterated polymer gels for measuring anisotropic NMR parameters with strongly reduced artefacts
  The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning
  Perspectives on NMR in drug discovery: a technique comes of age
  CIPSM Coordinator Horst Kessler wins Josef Rudinger Award
  YEAH! CIPSM-Junior-Group Leader Katja Strässer receives big €-EU-Grant
  A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation
  A structure refinement protocol combining NMR residual dipolar couplings and small angle scattering restraints
  Genome-associated RNA Polymerase II Includes the Dissociable Rpb4/7 Subcomplex*
  Backbone assignment of the UHM domain of Puf60 free and bound to five ligands
  N-Methylation of Peptides: A New Perspective in Medicinal Chemistry
  The structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicity
  Induction of Cell Polarization and Migration by a Gradient of Nanoscale Variations in Adhesive Ligand Spacing
  Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation
  Rational Design of Highly Active and Selective Ligands for the alpha-5-beta-1 Integrin Receptor
  Crystallization of RNA polymerase I subcomplex A14/A43 by iterative prediction, probing and removal of flexible regions
  The Role of 23S Ribosomal RNA Residue A2451 in Peptide Bond Synthesis Revealed by Atomic Mutagenesis
  Isothiocyanate-functionalized RGD peptides for tailoring cell-adhesive surface patterns
  Multiplexed Proteomics Mapping of Yeast RNA Polymerase II and III Allows Near-Complete Sequence Coverage and Reveals Several Novel Phosphorylation Sites
  The sweetest candy for the virus
  Introduction of Functional Groups into Peptides via N-Alkylation
  Translational Regulation via L11: Molecular Switches on the Ribosome Turned On and Off by Thiostrepton and Micrococcin
  1H, 13C, and 15N chemical shift assignments for the Eps15-EH2-stonin 2 complex
  The CLIP/CLAP-HSQC: Pure absorptive spectra for the measurement of one-bond couplings
  Phosphorus NMR Spectroscopy as a Versatile Tool for Compound Library Screening
  Improving Oral Bioavailability of Peptides by Multiple N-Methylation: Somatostatin Analogues
  Role of Ser-340 and Thr-341 in Transmembrane Domain IX of the Na+/Proline Transporter PutP of Escherichia coli in Ligand Binding Transport
  Structure of an Archaeal RNA Polymerase
  Conformational Preference and Potential Templates of N-Methylated Cyclic Pentaalanine Peptides
  Structure of Eukaryotic RNA Polymerases
  Assessment of αvβ3 Integrin Expression after Myocarcdial Infarction by Positron Emission Tomography
  Structure–function analysis of the RNA polymerase cleft loops elucidates initial transcription, DNA unwinding and RNA displacement
  The C-Terminal Regulatory Domain Is the RNA 5`-Triphosphate Sensor of RIG-I
  Structure–system correlation identifies a gene regulatory Mediator submodule
  Structure of the Eps15–stonin2 complex provides a molecular explanation for EH-domain ligand specificity
  Efficient factor VIII affinity purification using a small synthetic ligand
  Single-molecule tracking of mRNA exiting from RNA polymerase II

2007

  Functional Architecture of RNA Polymerase I
  The membrane-integrated transcriptional activator CadC of Escherichia coli senses lysine indirectly via the interaction with the lysine permease LysP
  Site specific phosphorylation of yeast RNA polymerase I
  2008 Gottfried Wilhelm Leibniz Prize for CIPSM researcher Elena Conti
  Cryo-EM study of the spinach chloroplast ribosome reveals the structural and functional roles of plastid-specific ribosomal proteins
  Molecular basis of RNA-dependent RNA polymerase II activity
  Allowing an elite
  Seeing Cisplatin - Discerning how an anticancer drug meddles with replication, transcription
  Mechanism of transcriptional stalling at cisplatindamaged DNA
  Structural Aspects of RbfA Action during Small Ribosomal Subunit Assembly
  Bypass of DNA Lesions Generated During Anticancer Treatment with Cisplatin by DNA Polymerase Eta
  Multiple N-Methylation by a Designed Approach Enhances Receptor Selectivity
  Archaeal transcription: function of an alternative transcription factor B from Pyrococcus furiosus
  Structural Biology of RNA Polymerase III: Mass Spectrometry Elucidates Subcomplex Architecture
  J-ONLY-TOCSY: Efficient suppression of RDC-induced transfer in homonuclear TOCSY experiments using JESTER-1-derived multiple pulse sequences
  Specific Integrin Labeling in Living Cells Using Functionalized Nanocrystals
  High-Resolution Structure of a Na+/H+ Antiporter Dimer Obtained by Pulsed Electron Paramagnetic Resonance Distance Measurements
  Development of a Peptidomimetic Ligand for Efficient Isolation and Purification of Factor VIII via Affinity Chromatography
  Finding the right spot to start transcription
  Drosophilia microRNAs Are Sorted into Functionally Distinct Argonaute Complexes after Production by Dicer-1
  Multisubunit RNA Polymerases Melt Only a Single DNA Base Pair Downstream of the Active Site
  piRNAs-the ancient hunters of genome invaders
  The RGD motif in fi bronectin is essential for development but dispensable for fibril assembly
  U2AF-homology motif interactions are required for alternative splicing regulation by SPF45
  Structural basis for DNA duplex sepration by a superfamily-2 helicase
  DNA photodamage recognition by RNA polymerase II
  CPD Damage Recognition by Transcribing RNA Polymerase II




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TU München
MPG
Helmholz Muenchen
MPI of Neurobiology
MPI of Biochemistry