Dosage compensation and the global re-balancing of aneuploid genomes

Genome Biology, 2010, 8, doi:10.1186/gb-2010-11-8-216 published on 26.08.2010
Genome Biology, online article
Diploid genomes are exquisitely balanced systems of gene expression. The dosage-compensation systems that evolved along with monosomic sex chromosomes exemplify the intricacies of compensating for differences in gene copy number by transcriptional regulation.

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