Research Area B

2017

TOM9.2 Is a Calmodulin-Binding Protein Critical for TOM Complex Assembly but Not for Mitochondrial Protein Import in Arabidopsis thaliana

Assembly-induced folding regulates interleukin 12 biogenesis and secretion

New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Import of Soluble Proteins into Chloroplasts and Potential Regulatory Mechanisms

2016

Chloroplast differentiation in the growing leaves of Arabidopsis thaliana

The PPR protein SLOW GROWTH 4 is involved in editing of nad4 and affects the splicing of nad2 intron 1

Structural basis for ArfA–RF2-mediated translation termination on mRNAs lacking stop codons

The Chaperone Activity and Substrate Spectrum of Human Small Heat Shock Proteins

Covalently circularized nanodiscs for studying membrane proteins and viral entry

Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN

A humanized yeast proteasome identifies unique binding modes of inhibitors for the immunosubunit β5i

Plant-Specific Preprotein and Amino Acid Transporter Proteins Are Required for tRNA Import into Mitochondria

Natural-Product-Inspired Aminoepoxybenzoquinones Kill Members of the Gram-Negative Pathogen Salmonella by Attenuating Cellular Stress Response

Ycf1/Tic214 Is Not Essential for the Accumulation of Plastid Proteins

Importance of cycle timing for the function of the molecular chaperone Hsp90

Tunable Probes with Direct Fluorescence Signals for the Constitutive and Immunoproteasome

Characterization of a Cyanobacterial Haloperoxidase and Evaluation of its Biocatalytic Halogenation Potential

Allosteric Regulation Points Control the Conformational Dynamics of the Molecular Chaperone Hsp90

Nucleotide-Free sB-Raf is Preferentially Bound by Hsp90 and Cdc37 In Vitro

Plant mitochondria contain the protein translocase subunits TatB and TatC

Thylakoid Membrane Architecture in Synechocystis Depends on CurT, a Homolog of the Granal CURVATURE THYLAKOID1 Proteins

Members of the Hsp70 Family Recognize Distinct Types of Sequences to Execute ER Quality Control

Structure-Based Design of β5c Selective Inhibitors of Human Constitutive Proteasomes

BiPPred: Combined sequence- and structure-based prediction of peptide binding to the Hsp70 chaperone BiP

A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest

In vivo aspects of protein folding and quality control

OEP40: a Regulated Glucose-Permeable, β-Barrel Solute Channel in the Chloroplast Outer Envelope Membrane

The stringent factor RelA adopts an open conformation on the ribosome to stimulate ppGpp synthesis

Once upon a Time – Chloroplast Protein Import Research from Infancy to Future Challenges

Construction and evaluation of yeast expression networks by database-guided predictions

Rational Design of Proteasome Inhibitors as Antimalarial Drugs

The calmodulin-like proteins AtCML4 and AtCML5 are single-pass membrane proteins targeted to the endomembrane system by an N-terminal signal anchor sequence

The Arabidopsis Protein CGLD11 Is Required for Chloroplast ATP Synthase Accumulation

A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome

Failure of RQC machinery causes protein aggregation and proteotoxic stress

Translation regulation via nascent polypeptide-mediated ribosome stalling

Folding and assembly of the large molecular machine Hsp90 studied in single-molecule experiments

A Stable Mutant Predisposes Antibody Domains to Amyloid Formation through Specific Non-Native Interactions

Sequential Inactivation of Gliotoxin by the S-Methyltransferase TmtA

Structure and function of α-crystallins: Traversing from in vitro to in vivo

Vast majority of the proteasome core structures added to the wwPDB archive from CIPSM investigator Michael Groll’s group

2015

Structure of the hypusinylated eukaryotic translation factor eIF-5A bound to the ribosome

ATP hydrolysis by the viral RNA sensor RIG-I prevents unintentional recognition of self-RNA

The activity of protein phosphatase 5 towards native clients is modulated by the middle- and C-terminal domains of Hsp9

Selective Inhibition of the Immunoproteasome by Structure-Based Targeting of a Non-catalytic Cysteine

Reversible Inhibitors Arrest ClpP in a Defined Conformational State that Can Be Revoked by ClpX Association

Structure of the Dioxygenase AsqJ: Mechanistic Insights into a One-Pot Multistep Quinolone Antibiotic Biosynthesis

The Antibody Light-Chain Linker Is Important for Domain Stability and Amyloid Formation

Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites

Targeted Delivery of Proteasome Inhibitors to Somatostatin-Receptor-Expressing Cancer Cells by Octreotide Conjugation

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1

The chaperone αB-crystallin uses different interfaces to capture an amorphous and an amyloid client

In vitro analyses of mitochondrial ATP/phosphate carriers from Arabidopsis thaliana revealed unexpected Ca2+-effects

Translational arrest by a prokaryotic signal recognition particle is mediated by RNA interactions

Locking GTPases covalently in their functional states

Azobenzene-based inhibitors of human carbonic anhydrase II

daf-41/p23: A Small Protein Heating Up Lifespan Regulation

Covalent Protein Labeling by Enzymatic Phosphocholination

The extreme Albino3 (Alb3) C terminus is required for Alb3 stability and function in Arabidopsis thaliana

Atomic-Resolution Structures of Discrete Stages on the Reaction Coordinate of the [Fe4S4] Enzyme IspG (GcpE)
The Chaperone Activity of the Developmental Small Heat Shock Protein Sip1 Is Regulated by pHDependent Conformational Changes
Conformational processing of oncogenic v-Src kinase by the molecular chaperone Hsp90
Macyranones: Structure, Biosynthesis, and Binding Mode of an Unprecedented Epoxyketone that Targets the 20S Proteasome
Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism
Systematic Analyses of Substrate Preferences of 20S Proteasomes Using Peptidic Epoxyketone Inhibitors

Role of the cytosolic loop C2 and the C-terminus of YidC in ribosome binding and insertion activity

A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation

A Minimal β-Lactone Fragment for Selective β5c or β5i Proteasome Inhibitors

Widespread Proteome Remodeling and Aggregation in Aging C. elegans

Phosphomimicking within the transit peptide of pHCF136 leads to reduced photosystem II accumulation in vivo

Structure of the Bacillus subtilis 70S ribosome reveals the basis for species-specific stalling
Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution

Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules

YCF1: A Green TIC?

Scalable Production in Human Cells and Biochemical Characterization of Full-Length Normal and Mutant Huntingtin
A Mass Spectrometry Platform for a Streamlined Investigation of Proteasome Integrity, Posttranslational Modifications, and Inhibitor Binding
Identification of cleavage sites and substrate proteins for two mitochondrial intermediate peptidases in Arabidopsis thaliana

AAA+ chaperones and acyldepsipeptides activate the ​ClpP protease via conformational control

Oep23 forms an ion channel in the chloroplast outer envelope
Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914
FAX1, a Novel Membrane Protein Mediating Plastid Fatty Acid Export
Structure and Mechanism of the Caseinolytic Protease ClpP1/2 Heterocomplex from Listeria monocytogenes
Redox meets protein trafficking
Indolo-Phakellins as β5-Specific Noncovalent Proteasome Inhibitors

2014

The charged linker of the molecular chaperone Hsp90 modulates domain contacts and biological function
Hop/Sti1 phosphorylation inhibits its co-chaperone function
Molecular Perspectives on Protein Adenylylation
Structural characterization of the substrate transfer mechanism in Hsp70/​Hsp90 folding machinery mediated by ​Hop
Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation
α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner
Receptor-Bound Conformation of Cilengitide Better Represented by Its Solution-State Structure than the Solid-State Structure
Selective Inhibition of the Immunoproteasome by Ligand-Induced Crosslinking of the Active Site
Artificial Accelerators of the Molecular Chaperone Hsp90 Facilitate Rate-Limiting Conformational Transitions
Interactions of the natural product kendomycin and the 20S proteasome
A Residue-specific Shift in Stability and Amyloidogenicity of Antibody Variable Domains
α-Keto Phenylamides as P1′-Extended Proteasome Inhibitors
The Formation of Pyrroline and Tetrahydropyridine Rings in Amino Acids Catalyzed by Pyrrolysine Synthase (PylD)
The Legionella longbeachae Icm/Dot Substrate SidC Selectively Binds Phosphatidylinositol 4-Phosphate with Nanomolar Affinity and Promotes Pathogen Vacuole-Endoplasmic Reticulum Interactions
Structure-Based Design of β1i or β5i Specific Inhibitors of Human Immunoproteasomes
Protein Folding by Interaction
Differential global structural changes in the core particle of yeast and mouse proteasome induced by ligand binding
Enzyme Inhibition by Hydroamination: Design and Mechanism of a Hybrid Carmaphycin-Syringolin Enone Proteasome Inhibitor
Principles and engineering of antibody folding and assembly
Reaction Mechanism of Adenylyltransferase DrrA from Legionella pneumophila Elucidated by Time-Resolved Fourier Transform Infrared Spectroscopy
The structural analysis of shark IgNAR antibodies reveals evolutionary principles of immunoglobulins
Induced-Fit Mechanism in Class I Terpene Cyclases
Insights into the Binding of Pyridines to the Iron−Sulfur Enzyme IspH

GroEL/ES Chaperonin Modulates the Mechanism and Accelerates the Rate of TIM-Barrel Domain Folding

Leucine-Rich Repeat Kinase 2 Binds to Neuronal Vesicles through Protein Interactions Mediated by Its C-Terminal WD40 Domain
Molecular basis for erythromycin-dependent ribosome stalling during translation of the ErmBL leader peptide
Modulation of the Hsp90 Chaperone Cycle by a Stringent Client Protein
Harnessing the Evolvability of Tricyclic Microviridins To Dissect Protease–Inhibitor Interactions
Versatile C3-symmetric scaffolds and their use for covalent stabilization of the foldon trimer
The role of the hypervariable C-terminal domain in Rab GTPases membrane targeting
The structure of the N-terminal domain of the Legionella protein SidC
Diversity and plasticity in Rab GTPase nucleotide release mechanism has consequences for Rab activation and inactivation
A new system for naming ribosomal proteins
Systematic Comparison of Peptidic Proteasome Inhibitors Highlights the α-Ketoamide Electrophile as an Auspicious Reversible Lead Moti
Phosphorylation of Arabidopsis transketolase at Ser428 provides a potential paradigm for the metabolic control of chloroplast carbon metabolism
Direkte Modulation von Rab-GTPase-Effektor-Wechselwirkungen
Hedycaryol Synthase in Complex with Nerolidol Reveals Terpene Cyclase Mechanism
Pseudilins: Halogenated, Allosteric Inhibitors of the Non-Mevalonate Pathway Enzyme IspD
Flavoenzyme-Catalyzed Formation of Disulfide Bonds in Natural Products
Omuralide and Vibralactone: Differences in the Proteasome- β-Lactone-γ-Lactam Binding Scaffold Alter Target Preferences
Exploring Adenylylation and Phosphocholination as Post-Translational Modifications
Applied techniques for mining natural proteasome inhibitors

2013

Exploring Adenylylation and Phosphocholination as Post-Translational Modifications
Quantification of Interaction Strengths between Chaperones and Tetratricopeptide Repeat Domain-containing Membrane Proteins
Disruption of Oligomerization and Dehydroalanine Formation as Mechanisms for ClpP Protease Inhibition
Regulated structural transitions unleash the chaperone activity of αB-crystallin
Intermediates in the Guanine Nucleotide Exchange Reaction of Rab8 Protein Catalyzed by Guanine Nucleotide Exchange Factors Rabin8 and GRAB
Activation of Ran GTPase by a Legionella Effector Promotes Microtubule Polymerization, Pathogen Vacuole Motility and Infection
IspC as Target for Antiinfective Drug Discovery: Synthesis, Enantiomeric Separation, and Structural Biology of Fosmidomycin Thia Isosters
Structure and Subunit Topology of the INO80 Chromatin Remodeler and Its Nucleosome Complex
Mechanical Stability of the Antibody Domain CH3 Homodimer in Different Oxidation States
Identification of CP12 as a Novel Calcium-Binding Protein in Chloroplasts
Calmodulin-like protein AtCML3 mediates dimerization of peroxisomal processing protease AtDEG15 and contributes to normal peroxisome metabolism
Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy
Modulation of Small GTPases by Legionella
Structural and functional insights into caseinolytic proteases reveal an unprecedented regulation principle of their catalytic triad
Structure and Reaction Mechanism of Pyrrolysine Synthase (PylD)
Structure and function of Hip, an attenuator of the Hsp70 chaperone cycle
High-resolution structures of the IgM Fc domains reveal principles of its hexamer formation
Structures of the human and Drosophila 80S ribosome
Dimerized Linear Mimics of a Natural Cyclopeptide (TMC-95A) Are Potent Noncovalent Inhibitors of the Eukaryotic 20S Proteasome
Potent Proteasome Inhibitors Derived from the Unnatural cis-Cyclopropane Isomer of Belactosin A: Synthesis, Biological Activity, and Mode of Action
The chaperone Hsp90: changing partners for demanding clients
Structures of Fluoro, Amino, and Thiol Inhibitors Bound to the [Fe4S4] Protein IspH
Integration of the accelerator Aha1 in the Hsp90 co-chaperone cycle
Conformational Selection in Substrate Recognition by Hsp70 Chaperones
RabGEFs are a major determinant for specific Rab membrane targeting
Structural and Functional Analysis of the DEAF-1 and BS69 MYND Domains
Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites
The Regulatory Domain Stabilizes the p53 Tetramer by Intersubunit Contacts with the DNA Binding Domain
Mechanism of Rab1b deactivation by the Legionella pneumophila GAP LepB

2012

Catalytic mechanism of a mammalian Rab·RabGAP complex in atomic detail
Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT
Alternative bacterial two-component small heat shock protein systems
Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution
Arabidopsis thaliana Oxa proteins locate to mitochondria and fulfill essential roles during embryo development
Characterization of Enzymes from Legionella pneumophila Involved in Reversible Adenylylation of Rab1 Protein
Nucleus-Encoded Light-Harvesting Chlorophyll a/b Proteins are Imported Normally into Chlorophyll b-free Chloroplasts of Arabidopsis
The first alpha-helical domain of the vesicle-inducing protein in plastids 1 promotes oligomerization and lipid binding
Essential Role of VIPP1 in Chloroplast Envelope Maintenance in Arabidopsis
AtTPR7 is a chaperone-docking protein of the Sec translocon in Arabidopsis
Posttranslational modifications of Rab proteins cause effective displacement of GDP dissociation inhibitor
Depletion of leaf-type ferredoxin-NADP+ oxidoreductase results in the permanent induction of photoprotective mechanisms in Arabidopsis chloroplasts
The Hsp90 chaperone machinery: Conformational dynamics and regulation by co-chaperones
Conformational Switching of the Molecular Chaperone Hsp90 via Regulated Phosphorylation
Identification of a Hypochlorite-specific Transcription Factor from Escherichia coli
Programmed cell death in Ricinus and Arabidopsis: the function of KDEL cysteine peptidases in development
Reversible phosphocholination of Rab proteins by Legionella pneumophila effector proteins
Chloroplast-localized protein kinases: a step forward towards a complete inventory
The role of calcium in chloroplasts—an intriguing and unresolved puzzle
The architecture of functional modules in the Hsp90 co-chaperone Sti1/Hop
A toolset of aequorin expression vectors for in planta studies of subcellular calcium concentrations in Arabidopsis thaliana

2011

Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach
The phosphorylation state of chloroplast transit peptides regulates preprotein import
The plastid outer envelope protein OEP16 affects metabolic fluxes during ABA-controlled seed development and germination
Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach
The Arabidopsis calmodulin-like proteins AtCML30 and AtCML3 are targeted to mitochondria and peroxisomes, respectively
How kinesin-2 forms a stalk
Vibralactone as a Tool to Study the Activity and Structure of the ClpP1P2 Complex from Listeria monocytogenes
Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import
Firefly luciferase mutants as sensors of proteome stress
Structural analysis of the interaction between Hsp90 and the tumor suppressor protein p53
The Cytosolic Kinases STY8, STY17, and STY46 Are Involved in Chloroplast Differentiation in Arabidopsis
Protein Import into Chloroplasts: Dealing with the (Membrane) Integration Problem
Cytosolic HSP90 Cochaperones HOP and FKBP Interact with Freshly Synthesized Chloroplast Preproteins of Arabidopsis
Technical note: Brassica rapa: a new model plant for the isolation of chloro-plasts and biochemical studies
Total Chemical Synthesis of an Integral Membrane Enzyme: Diacylglycerol Kinase from Escherichia coli
Closing In on the Hsp90 Chaperone-Client Relationship
Mapping backbone and side-chain interactions in the transition state of a coupled protein folding and binding reaction
Protein disulfide isomerase isomerizes non-native disulfide bonds in human proinsulin independent of its peptidebinding activity
Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1
Reduction of disulphide bonds unmasks potent antimicrobial activity of human Beta-defensin 1
Substrate discrimination of the chaperone BiP by autonomous and cochaperone-regulated conformational transitions

2010

Approaching the Secrets of N-Glycosylation in Aspergillus fumigatus: Characterization of the AfOch1 Protein
Mixed Hsp90–cochaperone complexes are important for the progression of the reaction cycle
Ferredoxin:NADPH oxidoreductase is recruited to thylakoids by binding to a polyproline type II helix in a pH-dependent manner
The Heat Shock Response: Life on the Verge of Death
Protein import into chloroplasts—How chaperones feature into the game
Hsp12 Is an Intrinsically Unstructured Stress Protein that Folds upon Membrane Association and Modulates Membrane Function
Dosage compensation and the global re-balancing of aneuploid genomes
Dynamics of heat shock protein 90 C-terminal dimerization is an important part of its conformational cycle
Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ
A new concept for ferredoxin–NADP(H) oxidoreductase binding to plant thylakoids
Redox extends its regulatory reach to chloroplast protein import
Structural and Mechanical Hierarchies in the Alpha Crystallin Domain Dimer of the Hyperthermophilic Small Heat Shock Protein Hsp16.5
NETs formed by human neutrophils inhibit growth of the pathogenic mold Aspergillus fumigatus
Chaperonin-Catalyzed Rescue of Kinetically Trapped States in Protein Folding
Dissecting the Alternatively Folded State of the Antibody Fab Fragment
The plant PRAT proteins – preprotein and amino acid transport in mitochondria and chloroplasts
Intramembrane Proteolysis of Mgm1 by the Mitochondrial Rhomboid Protease Is Highly Promiscuous Regarding the Sequence of the Cleaved Hydrophobic Segment
Independent evolution of the core domain and its flanking sequences in small heat shock proteins
Farnesol misplaces tip-localized Rho proteins and inhibits cell wall integrity signalling in Aspergillus fumigatus
AfMkk2 is required for cell wall integrity signaling, adhesion, and full virulence of the human pathogen Aspergillus fumigatus
Evolution of Escherichia coli for growth at high temperatures
The Conformational Dynamics of the Mitochondrial Hsp70 Chaperone
An unlocking/relocking barrier in conformational fluctuations of villin headpiece subdomain
Regions Outside the Alpha-Crystallin Domain of the Small Heat Shock Protein Hsp26 Are Required for Its Dimerization
Asymmetric Activation of the Hsp90 Dimer by Its Cochaperone Aha1
Redox-regulation of protein import into chloroplasts and mitochondria: Similarities and differences.
The many faces of the mitochondrial TIM23 complex
Protein import into chloroplasts: The Tic complex and its regulation
Coupled chaperone action in folding and assembly of hexadecameric Rubisco
A coronin7 homolog with functions in actin-driven processes
Role of Tim50 in the Transfer of Precursor Proteins from the Outer to the Inner Membrane of Mitochondria

2009

How antibodies fold
ATPase domain and interdomain linker play a key role in aggregation of mitochondrial Hsp70 chaperone Ssc1
Superior Protective Immunity against Murine Listeriosis by Combined Vaccination with CpG DNA and Recombinant Salmonella enterica Serovar Typhimurium
Alb4 of Arabidopsis Promotes Assembly and Stabilization of a Non Chlorophyll-Binding Photosynthetic Complex, the CF1CF0–ATP Synthase
The mitA gene of Aspergillus fumigatus is required for mannosylation of inositol-phosphorylceramide, but is dispensable for pathogenicity
The charged linker region is an important regulator of Hsp90 function
The Folding Pathway of the Antibody VL Domain
Arabidopsis Tic62 and Ferredoxin-NADP(H) Oxidoreductase Form Light-Regulated Complexes That Are Integrated into the Chloroplast Redox Poise
Arabidopsis OBG-Like GTPase (AtOBGL) Is Localized in Chloroplasts and Has an Essential Function in Embryo Development
Calcium regulation in endosymbiotic organelles of plants
Formation of She2p tetramers is required for mRNA binding, mRNP assembly, and localization
Hsp90 is regulated by a switch point in the C-terminal domain
NMR Structure of a Monomeric Intermediate on the Evolutionarily Optimized Assembly Pathway of a Small Trimerization Domain
Structural and functional diversity in the family of small heat shock proteins from the parasite Toxoplasma gondii
The eye lens chaperone alpha-crystallin forms defined globular assemblies
Distinct roles of the two isoforms of the dynamin-like GTPase Mgm1 in mitochondrial fusion
Preprotein Import into Chloroplasts via the Toc and Tic Complexes Is Regulated by Redox Signals in Pisum sativum
Arabidopsis ATPase family gene 1-like protein 1 is a calmodulin-binding AAA+-ATPase with a dual localization in chloroplasts and mitochondria
A search for factors influencing etioplast - chloroplast transition
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g
An Unfolded CH1 Domain Controls the Assembly and Secretion of IgG Antibodies
Graduate School Life Science Munich (LSM)
Interaction of human heat shock protein 70 with tumor-associated peptides
The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis
Rapid Matrix-Assisted Refolding of Histidine-Tagged Proteins
Dissection of the ATP-induced conformational cycle of the molecular chaperone Hsp90
Calcium depletion and calmodulin inhibition affect the import of nuclear-encoded proteins into plant mitochondria
Protein import machineries in endosymbiotic organelles
Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import
The Native 3D Organization of Bacterial Polysomes
Role of Tim50 in the Transfer of Precursor Proteins from the Outer to the Inner Membrane of Mitochondria
Local conformational dynamics in alpha-helices measured by fast triplet transfer

2008

Interaction of tim23 with tim50 is essential for protein translocation by the mitochondrial tim23 complex
Characterization of TIC110, a channel-forming protein at the inner envelope membrane of chloroplasts, unveils a response to Ca2+ and a stromal regulatory disulfide bridge
Semisynthesis of a Glycosylphosphatidylinositol-Anchored Prion Protein
Import of preproteins into the chloroplast inner envelope membran
Rheology
Thirty years of protein translocation into mitochondria: Unexpectedly complex and still puzzling
The Actinome of Dictyostelium discoideum in Comparison to Actins and Actin-Related Proteins from Other Organisms
The structure of a folding intermediate provides insight into differences in immunoglobulin amyloidogenicity
Effect of Thioxopeptide Bonds on r-Helix Structure and Stability
Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria
Contribution of Trimeric Autotransporter C-Terminal Domains of Oligomeric Coiled-Coil Adhesin (Oca) Family Members YadA, UspA1, EibA, and Hia to Translocation of the YadA Passenger Domain and Virulence of Yersinia enterocolitica
Actin: its cumbersome pilgrimage through cellular compartments
Energetics of protein translocation into mitochondria
Unusual, Virulence Plasmid-Dependent Growth Behavior of Yersinia enterocolitica in Three-Dimensional Collagen Gels
Monitoring Protein Conformation along the Pathway of Chaperonin-Assisted Folding
TIC62 Redox-regulated Translocon Composition and Dynamics
Structural Dynamics of Archaeal Small Heat Shock Proteins
Activation of the Chaperone Hsp26 is Controlled by the Rearrangement of Its Thermosensor Domain

2007

Properties of the Kinesin-1 motor DdKif3 from Dictyostelium discoideum
A step dissected
A Grp on the Hsp90 Mechanism
CP250, a Novel Acidic Coiled Coil Protein of the Dictyostelium centrosome, Affects Growth, Chemotaxis, and the Nuclear Envelope
The ATP-ase cycle of the endoplamic chaperone GRP94
Protein transport in chloroplasts - targeting to the intermembrane space
CIPSM Movie
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TU München
MPG
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry