Comparison of cyclic RGD peptides for αvβ3 integrin detection in a rat model of myocardial infarction

EJNMMI Research, 2013, doi:10.1186/2191-219X-3-38, 3:38 published on 11.05.2013
EJNMMI Research, online article
Expression of αvβ3 integrin is increased after myocardial infarction as part of the repair process. Increased expression of αvβ3 has been shown by molecular imaging with 18F-galacto-RGD in a rat model. The 68Ga-labelled RGD compounds 68Ga-NODAGA-RGD and 68Ga-TRAP(RGD)3 have high specificity and affinity, and may therefore serve as alternatives of 18F-galacto-RGD for integrin imaging.  

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TU München
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Helmholtz München
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