Histone glutamine methylation afFACTing rDNA transcription

Cell Research, 2014, doi:10.1038/cr.2014.22, 24:261–262. published on 14.02.2014
Cell Research, online article
Chemical modifications of histone proteins directly and indirectly affect chromatin structure and thereby contribute to the multilayered control of diverse DNA-based processes. A recent study in Nature enriches this list of enzyme-dependent posttranslational histone marks by H2A glutamine methylation that appears to be dedicated to only one specific cellular process, the regulation of nucleolar rDNA transcription.

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