Research Area A - Publications 2017

ChemBioChem, Volume 18, Issue 13, Pages 1172–1176 , DOI: 10.1002/cbic.201600706
ChemBioChem, online article

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Mycobacterium tuberculosis (Mtb), the main causative agent of tuberculosis (Tb), has a complex cell envelope which forms an efficient barrier to antibiotics, thus contributing to the challenges of anti-tuberculosis therapy. However, the unique Mtb cell wall can be considered an advantage and be utilized to selectively label Mtb bacteria. Here we introduce three ...

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J. Phys. Chem. Lett., 2017, 8 (7), pp 1585–1592, DOI: 10.1021/acs.jpclett.7b00371
J. Phys. Chem. Lett., online article

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Twisted intramolecular charge transfer (TICT) formation in hemithioindigo photoswitches has recently been reported and constitutes a second deexcitation pathway complementary to photoisomerization. Typically, this behavior is not found for this type of photoswitches, and it takes special geometric and electronic conditions to realize it. Here we present a ...

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ACS Nano, 11 (2), pp 1498–1508, DOI: 10.1021/acsnano.6b06812
ACS Nano, online article

 

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Advances in the engineering of nanoparticles (NPs), which represent particles of less than 100 nm in one external dimension, led to an increasing utilization of nanomaterials for biomedical purposes. A prerequisite for their use in diagnostic and therapeutic applications, however, is the targeted delivery to the site of injury. Interactions between blood-borne ...

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PLoS ONE 12(1): e0170625, doi:10.1371/journal.pone.0170625
PLOS ONE, online article

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Protein-protein docking protocols aim to predict the structures of protein-protein complexes based on the structure of individual partners. Docking protocols usually include several steps of sampling, clustering, refinement and re-scoring. The scoring step is one of the bottlenecks in the performance of many state-of-the-art protocols. The performance of scoring ...

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