1H, 13C and 15N chemical shift assignments of IPSEΔNLS
Biomolecular NMR Assignments, 2011, DOI: 10.1007/s12104-011-9305-6, Volume 5, Number 2, 225-227 published on 24.04.2011
The interleukin-4-inducing principle from Schistosoma mansoni eggs (IPSE/alpha-1) is a major immunogenic component of schistosomes. It potently triggers the release of interleukin-4 from basophilic granulocytes in an IgE-dependent manner, suggesting a key function in the modulation of the host’s immune response to Schistosoma mansoni infection. Here we present the near complete assignment of an IPSE/alpha-1 variant, IPSEDNLS, which comprises the core domain of the protein.