Research Area C - Publications 2018

Nature, volume 556, pages386–390 (2018), doi:10.1038/s41586-018-0029-y
Nature, online article

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In the eukaryotic nucleus, DNA is packaged in the form of nucleosomes, each of which comprises about 147 base pairs of DNA wrapped around a histone protein octamer. The position and histone composition of nucleosomes is governed by ATP-dependent chromatin remodellers such as the 15-subunit INO80 complex. INO80 regulates gene expression, DNA repair and replication ...

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