Closing In on the Hsp90 Chaperone-Client Relationship

Structure, 2011, Vol. 19 Issue 4, 445-6 published on 13.04.2011
Structure, online article
The molecular chaperone Hsp90 regulates the activity and stability of a set of client proteins. Despite prog- ress in understanding its mechanism, the interaction of Hsp90 with clients has remained enigmatic. Now, in a recent issue of Molecular Cell, Street and coworkers present results that integrate the client in the Hsp90 chaperone cycle.  

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry