Reductive Dehydroxylation of Allyl Alcohols by IspH Protein

Angewandte Chemie, 2010, DOI: 10.1002/anie.201000833, Volume 49, Issue 47, pages 8802–8809 published on 04.10.2010
Angewandte Chemie, online article
The biosynthesis of natural products is a treasure trove of unusual reaction mechanisms. This Minireview summarizes recent work on the structure and mechanism of IspH protein, which catalyzes the reductive dehydroxylation of an allyl alcohol in a biosynthetic pathway leading to isoprenoid precursors.  

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry