Synthesis of Double-Bond-Substituted Hemithioindigo Photoswitches

Org. Lett., 20 (1), pp 232–235, DOI: 10.1021/acs.orglett.7b03574
Org. Lett., online article

 

A very short, high yielding, and convergent synthesis with broad substrate scope, enabling access to a very diverse range of hemithioindigos with 4-fold substituted double-bonds, is presented. With this method, carbon as well as nitrogen, oxygen, or sulfur based substituents can easily be introduced, delivering a wide array of novel structural motifs. Irradiation studies with visible light demonstrate proficient photoswitching properties of these chromophores at wavelengths up to 625 nm.
 

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