A primer to scaffolded DNA origami

Nature Methods, 2011, doi:10.1038/nmeth.1570, 8, 221–229 published on 25.02.2011
Nature Methods, online article
Molecular self-assembly with scaffolded DNA origami enables building custom-shaped nanometer-scale objects with molecular weights in the megadalton regime. Here we provide a practical guide for design and assembly of scaffolded DNA origami objects. We also introduce a computational tool for predicting the structure of DNA origami objects and provide information on the conditions under which DNA origami objects can be expected to maintain their structure.  

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry