Photocontrolled chignolin-derived β-hairpin peptidomimetics

Chem. Commun., 2015, DOI: 10.1039/C4CC10304A, 51, 4001-4004 published on 19.01.2015
Chem. Commun., online article
The synthesis of novel, chignolin-derived peptides comprising the azobenzene photoswitch [3-(3-aminomethyl)phenylazo]phenylacetic acid (AMPP) is reported. Reversible photoswitching behavior led to folding into β-hairpin-like structures, as unequivocally demonstrated by CD, FT-IR and NMR spectroscopy.

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