A New Mechanism of Phosphoregulation in Signal Transduction Pathways

Sci. Signal., 2009, 2 Issue 96, pe71 published on 10.11.2009
Science Signaling, online article
Histidine protein kinases and serine, threonine, or tyrosine protein kinases play essential roles in signal transduction in prokaryotes and eukaryotes. A third type of protein kinase, an arginine protein kinase, has been identified. McsB of Bacillus subtilis hosphorylates the heat shock transcriptional regulator CtsR and can be regarded as the founding member of arginine protein kinases.

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry