Proteomic workflow for analysis of archival formalin-fixed and paraffin-embedded clinical samples to a depth of 10 000 proteins

PROTEOMICS - Clinical Applications, 2013, DOI: 10.1002/prca.201200046, Volume 7, Issue 3-4, pages 225–233, published on 15.04.2013

PROTEOMICS Clinical Applications, online article

Archival formalin-fixed and paraffin-embedded clinical samples represent a very diverse source of material for proteomic investigation of diseases, often with follow-up patient information. Here, we describe an analytical workflow for analysis of laser-capture microdissected formalin-fixed and paraffin-embedded samples that allows studying proteomes to a depth of 10 000 proteins per sample.  

TU München
Helmholtz München
MPI of Neurobiology
MPI of Biochemistry